At the same time, the New York Times has said in its report that the company has announced that none of the volunteers who came forward for the vaccine have complained of any disease after the trial, nor have there been any deaths, thus ZyCoV. -D has become the first DNA-based vaccine to work against Kovid-18. Its third phase trial was held at 50 places across the country and 28000 people participated in it. The company has said that the trial was done during the peak of the second wave and it was expected that it would work against the delta variant. Not only this, this vaccine was also adopted on children up to the age of 12-18 and they have been found safe.
Recent reports say that the drug regulator has sought additional data from the company and after being fully satisfied, this vaccine can be released in August. In this way, after Bharat Biotech’s Covaccine, it will become the second fully developed vaccine in India.
Which category of vaccine?
Zydus vaccine falls under the category of genetic or nucleic acid vaccine. Part of the virus’s genetic information is inserted into the body, which prompts cells to produce an element of the virus that the immune system recognizes and attacks it with antibodies. This is the first time that a genetic vaccine has been developed for humans. Gavi, an organization working to deliver vaccines to poor countries, says – Many DNA vaccines have been brought for use on animals, such as the vaccine for horses brought against West Nile virus.
What will be the dose dose of the vaccine?
While most covid vaccines are taking only two doses (except for the one from Johnson & Johnson, which takes a single dose), ZyCoV-D is said to be three doses, which will be given over an interval of four weeks. . However, the company says that it has also assessed two doses with 3 mg, which has the same effect as three doses.
Along with this, this vaccine is intradermal, which means that there will be no need for a needle. Because of this, the risk of side effects will also be reduced. This is what the company says. There is an injection in it, but it is not applied very deeply, it is applied in the upper part of the skin. It can be kept in 2-8 degree Celsius temperature. Apart from Zydus, now many other companies of the world are also considering DNA vaccine such as Japanese company AnGes and American company Inovio.
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