New way to treat leukemia: AML Acute Myeloid Leukemia is a malignant cancer of the white blood cells (WBC), for which there are few effective treatments. Researchers have created a new Study discovered that AML cells depend on a protein called SCP4 for survival. CSHL of America (Cold Spring Laboratory in America) Professor Christopher Vakoc And Sofya Polyanskaya, a former graduate student, has explored a possible new therapeutic approach for the disease. SCP4 is a type of protein that regulates the activity of cells by removing phosphate from other proteins. Another type of protein, called a kinase, holds the phosphate back. The number of phosphates added or subtracted from a protein (phosphorylation level) determines its activities.
Sofya Polyanskaya discovered that SCP4 binds to one or two of its kind kinases, known as STK35 and PDIK1L. Phosphate and kinase must work together for AML cells to survive. In such a situation, if the gene that produces SCP4 is inactivated, cancer cells can be destroyed.
What is Leukemia?
Blood cell cancer is also called leukemia. Blood cells have broad categories and they include WBCs (white blood cells), platelets and RBCs (red blood cells). of webMD news According to Leukemia usually refers to white blood cell cancer.
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WBCs are considered essential elements of the immune system. They protect the body from invading viruses, fungi and bacteria in addition to alien substances and abnormal cells. WBCs are unable to do their job when they are affected by leukemia. They divide rapidly and develop into normal cells.
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disease progresses slowly
Once they are formed, WBCs continue to circulate in the lymph and blood throughout the body, with higher concentrations in the spleen and lymph nodes. Leukemia can be chronic or acute in onset. Cancer cells multiply rapidly in the acute type of leukemia. In the case of chronic leukemia, the disease progresses slowly and the initial symptoms can be quite mild. The type of cell can also be the basis for classification for leukemia. Leukemia includes myeloid cells or myelogenous leukemia which is very severe. Monocytes or granulocytes are composed of immature cells or myeloid cells. Lymphocytic leukemia involves lymphocytes.
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