Diabetes During diabetes, insulin hormone in the body stops, due to which many changes take place in the body. One of these is damage to the nerve, that is, nerve damage. This affects the digestive placenta and may cause constipation. In addition to constipation, diabetes patients include problems such as fatigue, weight loss, blurred vision and always feeling thirsty, frequent urination at night. Irritable Bowel Syndrome: Irritable bowel syndrome (IBS) may also cause constipation. No exact cause of Irritable Bowel Syndrome is yet to be understood, but it is caused by failure of your brain and intestine to adjust. Other symptoms are stomach aches and cramps, bloating, too much flatulence, sometimes sudden diarrhea, mucus. Anxiety and depression: When you take a lot of stress, your body works very differently. During this time your sympathetic nervous system becomes active, which means that the digestion stops. Depression can also be a cause of constipation. Many times in depression, people stay in bed all day due to suicidal thoughts, hopelessness, fatigue, due to which their digestion is affected and physical activities are stopped which become the cause of constipation.